http://ependymoma-cancer.com Just another WordPress weblog Thu, 17 Apr 2008 15:36:36 +0000 http://backend.userland.com/rss092 en Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests heterogeneity. We define a newly recognized subset of ependymal tumors, the trisomy 19 ependymoma. Histologically, they are compact lesions characterized by a ... http://ependymoma-cancer.com/2008/04/17/trisomy-19-ependymoma-a-newly-recognized-genetico-histological-association-including-clear-cell-ependymoma/ OBJECTIVE AND IMPORTANCE  Extraventricular ependymomas account for 50% of supratentorial ependymomas. Some tumors may extend to the gray matter reaching the pial surface, but pure cortical ependymomas are uncommon. Here, we report three patients with supratentorial intracortical ependymoma. CLINICAL PRESENTATION: We reviewed the clinicopathological findings of all patients operated on for ... http://ependymoma-cancer.com/2008/04/17/supratentorial-cortical-ependymoma-report-of-three-cases/ Ependymomas are central nervous system (CNS) tumours that originate from the wall of the ventricular system along the entire craniospinal axis. Although ependymomas from different regions of the CNS are histologically similar, they are clinically) and genetically distinct, suggesting that they represent a collection of different diseases. Intracranial ependymomas often ... http://ependymoma-cancer.com/2008/04/17/stem-cells-of-ependymoma/ A new study shows that long-term survivors of childhood leukemia and brain tumors are at increased risk of stroke well after their cancer treatment has ended, and that this risk is higher among those who were treated with a particular type of radiation therapy. The research, conducted as part of ... http://ependymoma-cancer.com/2008/04/17/childhood-leukemia-and-brain-tumor-survivors-at-increased-risk-of-stroke-later-in-life/ Cancer stem cells (CSC) are recently proposed to be the cancer initiating cells responsible for tumorigenesis and contribute to cancer resistance. Advances have been made in identifying and enriching CSC in leukemia and several solid tumors, including breast, brain and lung cancers. These studies suggest that, like normal stem cells, ... http://ependymoma-cancer.com/2008/04/17/cancer-stem-cells/ "Identifying the cancer stem cell and the evolutionarily conserved genetic programs underlying self-renewal in ERMS will likely lead to new insights into how to destroy these cell types in established malignancies," explains Dr. Zon. Rhabdomyosarcoma (RMS) is an aggressive cancer that arises from a primitive skeletal muscle cell called a "rhabdomyoblast". ... http://ependymoma-cancer.com/2008/04/17/pediatric-cancer-stem-cell-identified-understanding-the-origin-of-erms/ Myxopapillary ependymomas (MPEs) are low-grade neuroepithelial tumors typically occurring in the conus - cauda equina - filum terminale region. Limited molecular and cytogenetic analysis of MPEs has not demonstrated consistent abnormalities. In an attempt to clarify the chromosomal status of these tumors and identify commonly aberrant regions in the genome ... http://ependymoma-cancer.com/2008/04/17/structural-genomic-abnormalities-of-chromosomes-9-and-18-in-myxopapillary-ependymomas/ Report of Three Cases and Review of the Literature The clinical, microscopic, immunohistochemical, and ultrastructural features of three carcinoid tumors of the presacral region are reviewed. All tumors occurred in young women and did not involve the rectum. The predominant microscopic pattern was trabecular. The differential diagnosis included paraganglioma and myxopapillary ... http://ependymoma-cancer.com/2008/04/17/presacral-carcinoid-tumors/ Cancers are composed of heterogeneous cell populations, including highly proliferative immature precursors and differentiated cells, which may belong to different lineages. Recent advances in stem cell research have demonstrated the existence of tumour-initiating, cancer stem cells (CSCs) in non-solid and solid tumours. These cells are defined as CSCs because they ... http://ependymoma-cancer.com/2008/04/17/possibilities-of-new-therapeutic-strategies/ For both intracranial and spinal cord primary lesions, as complete a resection as possible is attempted (8). Progression-free survival is improved if radiation therapy is given, with doses of at least 45 Gy being employed (7). The optimal radiation volume for intracranial primary lesions is controversial. It is reasonable to ... http://ependymoma-cancer.com/2008/04/17/classically-tumor-grade-and-extent-of-surgery-have-been-thought-to-be-the-most-important-prognostic-factors-1234-more-recently-other-factors-including-tumour-site-5-radiation-therapy-6-a/